Think You May Have
Early Tooth Decay?

There may be a window to act before a cavity forms.

See whether CrystLCare™ Regeneration+ may be appropriate for you.

Tooth Decay Doesn't Start With a Hole

Before a cavity ever forms, teeth quietly lose minerals below the enamel surface. Catch it in that window, and there may be a way to help your tooth rebuild without a drill.

Smiling man holding a box of CrystLCare Regeneration dissolvable dental strips
CrystLCare Pro Biorestorative Fluoride-Plus treatment pack

What Is CrystLCare™ Regeneration+?

CrystLCare™ Regeneration+ is an Rx-Only, topical treatment for early tooth decay. It’s a small, dissolvable strip that delivers calcium, phosphate and fluoride, the natural building blocks of tooth enamel, to areas where your enamel needs them most using innovative targeting technology.

It's prescribed by a dental professional after an evaluation, and part of your treatment continues comfortably at home.

Easy-to-Use Home Application
Prescription Included
Dentist-Reviewed & Approved
Ships to Your Door

How Does It Work?

01
Dissolvable strip applied directly over the affected area of a tooth
STEP 1

Apply

A thin, dissolvable strip is placed directly over the affected area of the tooth.

02
Calcium phosphate and fluoride released from the dissolving strip onto the tooth
STEP 2

Target

As the strip dissolves it releases submicron starch particles containing calcium, phosphate and fluoride. These particles are targeted right to where the tooth needs them.

03
Minerals supporting natural remineralization and strengthening of weakened enamel
STEP 3

Form Enamel Mineral

The bioactive mineral ions are released from the particles by salivary enzymes and crystallize to form fluorapatite, a strong acid-resistant form of enamel.

Who Is It For

Is CrystLCare™ Regeneration+ Right for You?

CrystLCare™ Regeneration+ may be worth discussing with a dental professional if you've been told you have, or notice, any of the following. A dental evaluation is required.

1
Early Tooth Decay
  • Sometimes described as the very first stage of a cavity.
2
“Watch” Area
  • A spot your dentist is keeping an eye on, often early tooth decay.
3
Early / Incipient Caries Lesion
  • Also called a “non-cavitated” caries lesion.
4
White Spot Lesions
  • Chalky white patches on the tooth surface caused by loss of minerals from the outer enamel. Often represent the very first stage of tooth decay.
5
Orthodontic White Spots
  • White spots that appeared around braces or aligners.
6
Non-Cavitated Lesions
  • Tooth decay that has not yet formed a cavity (hole).

Talk with a dental professional to determine whether CrystLCare™ Regeneration+ is appropriate for you.

Start Online Consultation

What Does Treatment Look Like?

1
Dental professional evaluating a patient's teeth for CrystLCare Regeneration+ treatment

Dental Evaluation

A dental professional checks whether early treatment is appropriate for you.

2
Dental professional applying the first CrystLCare Regeneration+ strip

Professional Initiation

Your first strip is applied during your dental visit.

3
Patient applying CrystLCare Regeneration+ strip at home as directed

At-Home Use, as Directed

You continue applying strips at home, following your dental professional's instructions.

4
Dental professional conducting follow-up and reassessment during CrystLCare treatment

Follow-Up & Reassessment

Your dental professional monitors the area as part of your ongoing care.

How to Use Application Instructions

Once your dental professional has started your treatment, here's how to continue at home. Always follow your dental professional's specific instructions for frequency and duration.

Clean and prepare teeth before applying CrystLCare Regeneration+ strip
1

Clean & Prepare

Brush teeth with toothpaste, rinse with water, and floss before use.

Open CrystLCare Regeneration+ pouch and remove the dissolvable strip
2

Open & Remove

Dry hands first. Open the pouch by pulling apart the sealed end. Remove the strip right before use.

Moisten teeth with water before applying CrystLCare Regeneration+ strip
3

Moisten

Moisten teeth with water.

Apply CrystLCare Regeneration+ strip to the affected tooth area
4

Apply

Place either side of the strip onto the affected area. Fold excess behind or around the tooth and press gently until it adheres. Remoisten and reposition if needed.

Wait at least 3 minutes while the CrystLCare Regeneration+ strip dissolves
5

Wait (3 min)

Leave in place for at least 3 minutes. The strip is dissolvable — do not swallow it whole.

Avoid eating and drinking for 30 minutes after using CrystLCare Regeneration+
6

Protect (30 min)

Spit out any excess if you'd like. Don't eat or drink for 30 minutes.

Follow your dental professional's instructions for continued CrystLCare Regeneration+ treatment
7

Use as Directed

Follow your dental professional's directions for how often and how long to continue treatment.

Two Products: Two Levels of Care

Choose the level of mineral support that fits your dental needs.

OVER-THE-COUNTER

CrystLCare™ Biorestorative, Fluoride-Free

Fluoride-free mineral support designed for everyday dental sensitivity and enamel maintenance.

Type
Over-the-counter
Active Minerals
Calcium + Phosphate
Mechanism
Forms hydroxyapatite
crystals
Sensitivity Relief
Yes Enhanced
Enamel Remineralization
Yes
Caries Prevention
Supports remineralization
Requires Prescription
No
Best For
Sensitivity, Enamel Maintenance
Prescription
FLUORIDE-PLUS

CrystLCare™ Regeneration+

Advanced fluoride-plus mineral support for enamel repair, treatment of early tooth decay and cavity prevention

Type
Prescription (Rx-Only)
Active Minerals
Calcium + Phosphate + Fluoride
Mechanism
Forms stronger, more acid-resistant fluorapatite crystals
Sensitivity Relief
Yes
Enamel Remineralization
Yes Enhanced mineral delivery
Caries Prevention
Active cavity prevention with fluoride
Requires Prescription
Yes dentist review included
Best For
Treatment of early tooth decay and cavity prevention

Already Have a CrystLCare™ Prescription?

Choose the next step based on whether you already have a prescription or still need a dental evaluation.

CrystLCare at-home treatment instructions
HAVE A PRESCRIPTION

Yes

Head straight to your at-home application instructions.

Buy Now
Dental professional evaluating a patient for CrystLCare treatment
NEED AN EVALUATION

No

Start a dental evaluation to find out if CrystLCare™ may be right for you.

Take an Appointment

Don't Have a Diagnosis Yet?

If you have concerns about early tooth decay but haven't been evaluated, here are three ways to get started.

Patient uploading photos of teeth for dental review

Upload Photos for Dental Review

Share photos of your teeth for a dentist to review.

Online teledental evaluation with a dental provider

Get a Teledental Evaluation

Talk with an online dental provider about your concerns.

Patient finding an in-person dentist

Find a Dentist

Prefer an in-person visit? We'll help you find one.

Have questions?

Get answers

A non-invasive, Rx-Only treatment for early tooth decay. A dissolvable strip delivers calcium, phosphate and fluoride ions to where they are needed most, to help restore enamel mineral in the tooth subsurface (i.e., better than fluoride, which only affects the extreme upper surface layer).

Yes. CrystLCare™ Regeneration+ is available by prescription only, after a dental professional evaluates your teeth and confirms it's appropriate for you.

Both use the same patented nanotechnology to deliver minerals to damaged tooth structure. CrystLCare™ Biorestorative is designed for quick and effective sensitivity relief. CrystLCare™ Regeneration+ adds fluoride to the formulation, creating fluorapatite crystals, which are stronger and more acid-resistant than the hydroxyapatite crystals formed by the fluoride-free version. CrystLCare™ Regeneration+ is a prescription product; the fluoride-free version is available over the counter.

People with early tooth decay, early (incipient) caries lesions, one or more “watch” areas, white spot lesions (including from braces or aligners), or non-cavitated lesions may be candidates subject to a dental evaluation. It's not appropriate for visibly broken or cavitated teeth, or dental emergencies.

Your dental professional applies the first strip during your visit. You then continue applying strips at home, following their specific instructions.

Yes after your dental professional initiates treatment in-office, you continue at home. Always follow the frequency and duration they prescribe for you.

Leave the strip in place for at least 3 minutes while it dissolves. Avoid eating or drinking for 30 minutes afterward.

The targeted mineral-delivery of CrystLCare™ products can also help occlude exposed dentinal tubules, which may provide relief from tooth sensitivity. Ask your dental professional whether this applies to you.

CrystLCare™ Regeneration+ is designed for early, non-cavitated decay, not for treating an existing cavity (i.e. not once it becomes a hole). If your tooth is visibly broken, cavitated, or painful, please see a dentist.

Use the evaluation request form to upload photos, request a teledental evaluation, or ask for a dentist referral - whichever is easiest for you.