OralDNA Salivary Testing

OralDNA® Salivary Testing

Precision Oral Pathogen Analysis for Personalized Care

OralDNA® testing identifies harmful oral pathogens, inflammation markers, and systemic connections—helping dentists create targeted treatment plans based on your unique saliva profile.

Advanced Oral Diagnostics That Change Lives

OralDNA Saliva Testing uses advanced microbiological DNA mapping to detect harmful bacteria, inflammatory markers, and oral-systemic health indicators. These insights go far beyond visual exams and traditional cleanings.

Oral bacteria influence gum disease, tooth decay, chronic inflammation, pregnancy outcomes, arthritis, immune imbalance, and even cognitive and heart health. Early detection helps protect long-term wellness.

OralDNA Testing Kit
OralDNA Salivary Testing

Beyond Visual Examination

Traditional dental exams only reveal what's visible to the eye missing hidden bacterial activity, genetic risks, and early infections. Dentulu’s advanced salivary diagnostics go deeper, identifying pathogens, genetic inflammation markers, and even HPV-related risks long before symptoms appear. By combining molecular insights with personalized treatment guidance, we help you prevent disease not just treat it after it starts.

Bacterial Type Detection

Which specific bacteria are causing your gum disease

Genetic Risk Factors

Your genetic predisposition to inflammation

Silent Infections

Detected before symptoms appear

Targeted Antibiotics

Matched to your specific pathogens

HPV-Related Risk

Screening for HPV-related oral cancer

Why OralDNA Testing Matters

OralDNA testing goes beyond traditional dental exams by identifying the specific bacteria and biomarkers that influence your oral and overall health. By understanding your unique microbiome profile, dentists can diagnose conditions earlier, personalize treatment plans, and help prevent future disease with far greater accuracy.

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Oral microbiome imbalance
Persistent bad breath causes
High-risk periodontal pathogens
Gum disease–causing bacteria
Caries-related bacteria
Systemic health indicators
Inflammation biomarkers
Pregnancy and immune-related risk factors

What’s Inside Your OralDNA Test Kit

Everything you need for safe, accurate at-home saliva collection is included in your OralDNA kit. Each component is pre-labeled, easy to use, and designed to ensure your sample stays stable during return shipping. Just follow the step-by-step guide, seal your sample, and drop it in the prepaid mailer for fast laboratory processing.

Our Comprehensive Test Menu

Discover Dentulu’s advanced salivary and genetic tests that reveal hidden causes of oral and systemic issues. Each test provides insights for early, personalized treatment, empowering your dentist to protect your oral health.

MyPerioPath®
What it tests:

11 specific periodontal pathogens

Who should test
  • Bleeding gums or deep pockets
  • Persistent bad breath
  • Before extensive dental work
  • Systemic inflammatory conditions
  • Annual monitoring
Results Include

Pathogen levels, risk score, antibiotic guidance

Key pathogens:
  • High-Risk: Aa, Pg, Td, Tf, Fn
  • Moderate-Risk: Cr, Ec, Pi, Pm
  • Low-Risk: Cs, En
OraRisk® HPV
What it tests:

51 types of Human Papillomavirus (HPV)

Who should test
  • Adults over 30
  • Multiple partners or HPV history
  • Oral lesions
  • Immunocompromised
Why It Matters

HPV-related oral cancers are up 225%

Identifies
  • High-risk types (16, 18, etc.)
  • Low-risk types
  • Multiple infections
Alert -2
What it tests:

IL-6 genetic marker related to inflammatory response

Who should test
  • People with Periodontal Disease,
  • Systemic illness
  • Bone Loss
  • Diabetes or Chronic Inflammation
Reveals
  • Risk-level classification for each pathogen
  • Inflammation risk
  • Periodontal disease severity
  • Treatment response forecast
OraRisk® Candida
What it tests:

9 Candida species

Who should test
  • Denture wearers
  • Dry mouth patients
  • Burning mouth syndrome
  • On meds or immunocompromised
Species

C. albicans, C. glabrata, C. tropicalis

+ 6 more

OraRisk® Caries
What it tests:

Cavity-causing bacteria

Who should test
  • Recurring cavities
  • Before orthodontics
  • Dry mouth patients
  • Planning pregnancy
Bacteria

Streptococcus mutans, S. sobrinus,

Lactobacillus

Simple Collection, Powerful Results

Experience a hassle-free testing process from start to finish. Our at-home kits are quick, comfortable, and clinically precise—no needles or dental visits required. With just a simple saline rinse, you can uncover vital oral health insights in days, not weeks. Every step is designed for convenience, accuracy, and total peace of mind.

1
Order Your Kit
  • Select the appropriate test(s) based on your symptoms or risk factors. Kits ship within 24 hours.
2
Easy Sample Collection
  • Swish with sterile saline for 30 seconds
  • Spit into the provided tube
  • No fasting required
  • Takes less than 5 minutes
3
Prepaid Shipping
  • Use the included FedEx label to send your sample to the lab. Tracking provided.
4
Rapid Results
  • Results in 7–10 business days
  • Secure online portal access
  • Detailed report with recommendations
  • Provider consultation available

Comprehensive Reporting That Guides Treatment

Every Dentulu report translates complex lab data into clear, actionable insights. From identifying harmful microbes to assessing your personalized risk profile, our reports empower both you and your provider to make informed, targeted care decisions. With science-driven recommendations, you'll receive a complete roadmap to restore balance, prevent recurrence, and protect your long-term oral and systemic health.

Pathogen Identification& Levels
  • Specific bacteria/viruses detected
  • Concentration levels (low, moderate, high)
  • Comparison to healthy ranges
Risk Assessment
  • Overall disease risk score
  • Individual pathogen risk analysis
  • Systemic health implications
Treatment Recommendations
  • Targeted antibiotic options
  • Natural antimicrobial alternatives
  • Probiotic suggestions
  • Lifestyle modifications
Clinical Considerations
  • Recommended follow-up testing
  • Suggested dental treatments
  • Medical referral recommendations

Evidence-Based Testing You
Can Trust

Published Research

  • Over 50 peer-reviewed studies validate OralDNA testing
  • Used in major universities and research institutions
  • FDA-cleared collection devices
  • CLIA-certified laboratory
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Evidence Testing

Take the First Step Toward Optimal Oral Health

Questions? Our Clinical Team is Here to Help

CLIA Certified Laboratory

FDA Cleared Collection Device

HIPAA Compliant

Call 888-905-0226
support@dentulu.com
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Have questions?

Get answers

OralDNA uses advanced qPCR technology with 99.9% accuracy for detecting pathogens, making it far more reliable than traditional culture methods.

Many medical insurance plans provide coverage when the test is linked to systemic or chronic conditions. We also supply correct coding to help maximize reimbursement.

For active infections: every 6–8 weeks after treatment.
For ongoing monitoring: every 6–12 months, depending on risk factors.

For the most accurate results, you should wait at least 2 weeks after completing antibiotics before testing.

No. OralDNA tests detect active oral infections such as bacteria and viruses. They do not assess human genetic traits or ancestry.

Yes, the tests are safe for all ages. Caries-related testing can be especially helpful for children who are prone to cavities.

While professional guidance is recommended, direct-to-consumer test options are available in most states.